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International Journal of Phytomedicine and Phytotherapy

Table 5 The comparison of the groups according to the dynamics of the symptom severity using the Mann – Whitney U-test

From: A randomized, open-label, multicentre, comparative study of therapeutic efficacy, preventive potential and tolerability of BNO 1030 extract, containing Althea root, Chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years

Parameter

Visit

Mann–Whitney U-test

Wilcoxon W

Z-statistics

P-value (two-sided)

Significant differencesa

Hyperaemia of the posterior wall

Day 1

7116.000

14,256.000

−0.047

0.962

Non-significant

Day 10

6345.500

13,485.500

−1.276

0.202

Non-significant

6 month

4619.000

11,759.000

−5.110

0.000

Significant

Hyperaemia of the tonsils

Day 1

6933.000

14,193.000

−0.404

0.686

Non-significant

Day 10

6785.500

13,688.500

−0.374

0.708

Non-significant

6 month

4509.000

11,530.000

−5.596

0.000

Significant

Swelling, plaque

Day 1

6845.000

13,985.000

−0.575

0.565

Non-significant

Day 10

6116.000

13,256.000

−1.779

0.075

Non-significant

6 month

4129.500

11,150.500

−6.485

0.000

Significant

Self-assessment of the patient

Day 1

6086.500

13,346.500

−2.011

0.044

Non-significant

Day 5

5942.000

13,082.000

−2.277

0.023

Significant

Day 10

5023.000

12,163.000

−3.908

0.000

Significant

Day 38

5468.500

12,608.500

−3.632

0.000

Significant

3 month

5124.500

12,264.500

−4.366

0.000

Significant

6 month

4072.000

11,212.000

−6.229

0.000

Significant

12 month

3945.000

11,085.000

−7.528

0.000

Significant

  1. aThe conclusion is drawn at the significance level of 0.05