Characterization of pharmacological properties of methanolic seed and stem bark extracts of Ziziphus mauritiana (BAU Kul) using in-vitro and in-vivo animal (Swiss albino male mice) model

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 4 IC₅₀values of DPPH, NO, LC₅₀, LC₉₀ values of brine shrimp lethality bioassays, % of clot lysis and % inhibition of hypotonic solution and heat induce hemolysis of the different extractives and standard

Extracts	Scavenging capacity assay, IC₅₀ (μg/ml)		Brine shrimp lethality bioassay (μg/ml)		Thrombolytic activity	% Inhibition of hemolysis ± SEM (membrane stabilizing potential)
Extracts	DPPH	NO	LC₅₀	LC₉₀	% of clot lysis	Hypotonic Solution	Heat Induce
SE	4.53^{a, b}	5.92^b	1.46^a	2.48	24.95	25.00 ± 1.56	34.79 ± 2.55
SBE	4.13^{a, b}	5.47^b	1.92^a	3.25	34.65	41.88 ± 1.58	46.03 ± 2.95
AA	3.43	4.77	–	–	–	–	–
VS	–	–	0.39	1.12	–	–	–
SK	–	–	–	–	66.38	–	–
DL	–	–	–	–	6.91%	–	–
ASA	–	–	–	–	–	64.24 ± 0.44	67.59 ± 1.46

[SE Seed Extract, SBE Stem Bark Extract, AA Ascorbic Acid, VS Vincristine Sulphate, SK Streptokinase, DL Distilled Water, ASA Acetyl Salicylic Acid. Data was expressed as Mean ± SEM (Standard error of Mean). t-test of two equal variance was done to analyze the data set. Values in the same column with different superscripts are significantly different from another, p˂0.05]