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Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Fig. 2 | Clinical Phytoscience

Fig. 2

From: Toxicity study and anti-trypanosomal activities of aqueous and methanol whole plant extracts of Brillantaisia owariensis on Trypanosoma brucei-induced infection in BALB/c mice

Fig. 2

Plate II (a-f): Toxicity of aqueous and methanol whole plant extracts of Brillantaisia owariensis on the histology of kidney organ in BALB/c mice-photomicrograph of kidney sections of mice. a Mild tubular adhesion and lymphocyte hyperplasia at doses of A10 mg/Kg/body weights of aqueous and methanol extracts. b Mild tubular necrosis at 100 mg/Kg aqueous extract, and moderate hepatic necrosis in mice orally administered 100 mg/Kg/ body weight of the methanol extracts. c Mild tubular necrosis in mice administered 1000 mg/kg aqueous and methanol extract. d Mild glomerular necrosis at 1600 mg/kg aqueous and methanol extract e moderate to mild lymphocyte hyperplasia at 2500 mg/Kg/ body weight of both aqueous and methanol extract. f Moderate tubular adhesion and moderate lymphocyte hyperplasia at 5000 mg/Kg/body weight of aqueous and methanol extracts. (H and E, X 400)

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