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International Journal of Phytomedicine and Phytotherapy

Table 1 In vivo anthelmintic effects of A. racemosus root extract* on H. diminuta infections in rats (n = 5)

From: Studies on the anthelmintic potentials of the roots of Asparagus racemosus willd. (Asparagaceae)

Treatment groups (mg/kgxdosexday)

EPG (mean ± SEM)

Percentage difference in EPG (A-B)

Worm count at necropsy (mean ± SEM)

Percentage reduction in worm count

Pre-treatment 18–20 days (A)

Post-treatment 26–28 days (B)

Control

22,318 ± 168

22,688 ± 194

1.63

5.0 ± 0.00

0

Plant extract

125 × 1 × 5

22,530 ± 148

15,399 ± 142b

− 31.65

4.2 ± 0.20

16

250 × 1 × 5

22,620 ± 126

13,643 ± 135b

− 39.68

4.0 ± 0.31

20

500 × 1 × 5

22,754 ± 109

10,494 ± 101b

− 53.88

3.8 ± 0.37

24

Praziquantel

5 × 1 × 5

22,850 ± 56.24

2952 ± 38.86b

−87.08

0.8 ± 0.20a

84

  1. *Administration of plant extract and praziquantel on days 21–25 post-inoculation with five cysticercoids/rat
  2. ap<0.001 as compared to control value, bp<0.001 as compared to pre-treatment period, one-way ANOVA, followed by Tukey’s test