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International Journal of Phytomedicine and Phytotherapy

Table 1 In vivo anthelmintic effects of A. racemosus root extract* on H. diminuta infections in rats (n = 5)

From: Studies on the anthelmintic potentials of the roots of Asparagus racemosus willd. (Asparagaceae)

Treatment groups (mg/kgxdosexday) EPG (mean ± SEM) Percentage difference in EPG (A-B) Worm count at necropsy (mean ± SEM) Percentage reduction in worm count
Pre-treatment 18–20 days (A) Post-treatment 26–28 days (B)
Control 22,318 ± 168 22,688 ± 194 1.63 5.0 ± 0.00 0
Plant extract
125 × 1 × 5 22,530 ± 148 15,399 ± 142b − 31.65 4.2 ± 0.20 16
250 × 1 × 5 22,620 ± 126 13,643 ± 135b − 39.68 4.0 ± 0.31 20
500 × 1 × 5 22,754 ± 109 10,494 ± 101b − 53.88 3.8 ± 0.37 24
Praziquantel
5 × 1 × 5 22,850 ± 56.24 2952 ± 38.86b −87.08 0.8 ± 0.20a 84
  1. *Administration of plant extract and praziquantel on days 21–25 post-inoculation with five cysticercoids/rat
  2. ap<0.001 as compared to control value, bp<0.001 as compared to pre-treatment period, one-way ANOVA, followed by Tukey’s test