Table 1 Inclusion and exclusion criteria

Inclusion criteria

 1. Age 20–48 years (both inclusive).

 2. Participants having BMI ≤ 30.

 3. Participants with normal blood pressure and fasting blood glucose.

 4. Participants understand the study procedures and provides signed informed consent to participate in the study.

Exclusion criteria

 1. History of cerebrovascular disease, heart attack, or angina at any time or on anti-coagulant or anti-platelet drugs on a daily basis for any conditions.

 2. Any previous hormonal treatment or treatment with fenugreek derived products in the previous 12 months.

 3. Participants with abnormal ECG, biochemical or hematological values.

 4. Any history of using estrogen or progestin containing products in the past 6 months of recruitment.

 5. History of breast, endometrial, other gynecological cancer at any period of life or other cancer within the last 5 years.

 6. Experiencing depression and/or receiving medication for such illness or disorders, receiving statins or other drugs known to impact on steroid hormone levels.

 7. Participants, who are smokers, tobacco or alcohol user.

 8. Participated in a clinical study with an investigational drug or biologic within the last 30 days.

 9. Use of any recreational drugs (cocaine, amphetamine, barbiturates, benzodiazepines, cannabinoids and morphine)

 10. History of clinically significant illness or any other medical disorder that may interfere with treatment, assessment or compliance with the protocol.

 11. Any condition that in opinion of the Investigator, does not justify the participants participation in the study.