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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of AKSS16-LIV01 on liver function test parameters across the groups in chronic ethanol-induced hepatic damage in mice

From: Antioxidant and immunomodulatory effect of AKSS16-LIV01 – a multi herbal formulation against ethanol induced liver dysfunction in mice

Parameters Normal Ethanol Ethanol + AKSS16-LIV01 (75) Ethanol+AKSS16-LIV01 (150) Ethanol+AKSS16-LIV01 (300) Ethanol +Silymarin(100) AKSS16-LIV01 (300)
BUN (mg/dl) 0.41 ± 0.02 0.72 ± 0.04# 0.58 ± 0.04* 0.67 ± 0.02* 0.46 ± 0.02** 0.54 ± 0.03* 0.46 ± 0.03*
Total Bilirubin (mg/dl) 0.12 ± 0.2 0.62 ± 0.11# 0.22 ± 0.09* 0.34 ± 0.08* 0.16 ± 0.09** 0.24 ± 0.08* 0.19 ± 0.11*
Direct Bilirubin (mg/dl) 0.06 ± 0.001 0.33 ± 0.07# 0.19 ± 0.002* 0.09 ± 0.003* 0.09 ± 0.002** 0.11 ± 0.005* 0.07 ± 0.002*
Alb (gr/dL) 3.48 ± 0.186 1.97 ± 0.036# 2.85 ± 0.12* 3.70 ± 0.11* 4.02 ± 0.14** 3.32 ± 0.15* 3.16 ± 0.13*
Alb/globulin 1.18 ± 0.141 0.54 ± 0.013# 0.81 ± 0.091* 0.91 ± 0.096* 1.21 ± 0.95** 1.04 ± 0.091* 0.98 ± 0.135*
  1. The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test