|
Parameters
|
Normal
|
Ethanol
|
Ethanol + AKSS16-LIV01 (75)
|
Ethanol+AKSS16-LIV01 (150)
|
Ethanol+AKSS16-LIV01 (300)
|
Ethanol +Silymarin(100)
|
AKSS16-LIV01 (300)
|
|---|
|
BUN (mg/dl)
|
0.41 ± 0.02
|
0.72 ± 0.04#
|
0.58 ± 0.04*
|
0.67 ± 0.02*
|
0.46 ± 0.02**
|
0.54 ± 0.03*
|
0.46 ± 0.03*
|
|
Total Bilirubin (mg/dl)
|
0.12 ± 0.2
|
0.62 ± 0.11#
|
0.22 ± 0.09*
|
0.34 ± 0.08*
|
0.16 ± 0.09**
|
0.24 ± 0.08*
|
0.19 ± 0.11*
|
|
Direct Bilirubin (mg/dl)
|
0.06 ± 0.001
|
0.33 ± 0.07#
|
0.19 ± 0.002*
|
0.09 ± 0.003*
|
0.09 ± 0.002**
|
0.11 ± 0.005*
|
0.07 ± 0.002*
|
|
Alb (gr/dL)
|
3.48 ± 0.186
|
1.97 ± 0.036#
|
2.85 ± 0.12*
|
3.70 ± 0.11*
|
4.02 ± 0.14**
|
3.32 ± 0.15*
|
3.16 ± 0.13*
|
|
Alb/globulin
|
1.18 ± 0.141
|
0.54 ± 0.013#
|
0.81 ± 0.091*
|
0.91 ± 0.096*
|
1.21 ± 0.95**
|
1.04 ± 0.091*
|
0.98 ± 0.135*
|
- The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test
