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International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of AKSS16-LIV01 on liver function test parameters across the groups in chronic ethanol-induced hepatic damage in mice

From: Antioxidant and immunomodulatory effect of AKSS16-LIV01 – a multi herbal formulation against ethanol induced liver dysfunction in mice

Parameters

Normal

Ethanol

Ethanol + AKSS16-LIV01 (75)

Ethanol+AKSS16-LIV01 (150)

Ethanol+AKSS16-LIV01 (300)

Ethanol +Silymarin(100)

AKSS16-LIV01 (300)

BUN (mg/dl)

0.41 ± 0.02

0.72 ± 0.04#

0.58 ± 0.04*

0.67 ± 0.02*

0.46 ± 0.02**

0.54 ± 0.03*

0.46 ± 0.03*

Total Bilirubin (mg/dl)

0.12 ± 0.2

0.62 ± 0.11#

0.22 ± 0.09*

0.34 ± 0.08*

0.16 ± 0.09**

0.24 ± 0.08*

0.19 ± 0.11*

Direct Bilirubin (mg/dl)

0.06 ± 0.001

0.33 ± 0.07#

0.19 ± 0.002*

0.09 ± 0.003*

0.09 ± 0.002**

0.11 ± 0.005*

0.07 ± 0.002*

Alb (gr/dL)

3.48 ± 0.186

1.97 ± 0.036#

2.85 ± 0.12*

3.70 ± 0.11*

4.02 ± 0.14**

3.32 ± 0.15*

3.16 ± 0.13*

Alb/globulin

1.18 ± 0.141

0.54 ± 0.013#

0.81 ± 0.091*

0.91 ± 0.096*

1.21 ± 0.95**

1.04 ± 0.091*

0.98 ± 0.135*

  1. The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test