Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 8 Effect of AKSS16-LIV01 onliver Lipid peroxidation, NO, iNOS levels and Hydroxyproline concentration in chronic ethanol-induced hepatic damage in mice

From: Antioxidant and immunomodulatory effect of AKSS16-LIV01 – a multi herbal formulation against ethanol induced liver dysfunction in mice

Parameters

Normal

Ethanol

Ethanol + AKSS16-LIV01 (75)

Ethanol+AKSS16-LIV01 (150)

Ethanol+AKSS16-LIV01 (300)

Ethanol +Silymarin(100)

AKSS16-LIV01 (300)

Lipid Peroxidation (nm/100 g tissue)

68.16 ± 3.52

182.16 ± 3.09

92.35 ± 2.14*

77.92 ± 1.47*

62.58 ± 2.52**

82.57 ± 1.67*

66.57 ± 0.99*

NO (μmol/mg protein)

0.64 ± 0.004

2.29 ± 0.002#

102.77 ± 0.005*

0.84 ± 0.004*

0.69 ± 0.006**

0.88 ± 0.007*

0.65 ± 0.002*

iNOS (U/mg protein)

0.32 ± 0.003

1.11 ± 0.002#

0.62 ± 0.005*

0.46 ± 0.006*

0.38 ± 0.003**

0.45 ± 0.005*

0.39 ± 0.003*

Hydroxyproline (mq/g)

0.42 ± 0.004

0.99 ± 0.004#

0.76 ± 0.006*

0.55 ± 0.003*

0.47 ± 0.002**

0.56 ± 0.004*

0.44 ± 0.005*

  1. The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test