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International Journal of Phytomedicine and Phytotherapy

Table 9 Effect of AKSS16-LIV01 on TNF α and TGF 1β levels in liver tissue in chronic ethanol-induced hepatic damage in mice

From: Antioxidant and immunomodulatory effect of AKSS16-LIV01 – a multi herbal formulation against ethanol induced liver dysfunction in mice

Parameters Normal Ethanol Ethanol + AKSS16-LIV01 (75) Ethanol+AKSS16-LIV01 (150) Ethanol+AKSS16-LIV01 (300) Ethanol + Silymarin (100) AKSS16-LIV01 (300)
TNF-α (pg/mg protein) 1411.91 ± 206.53 2344.77 ± 371.98# 1636.77 ± 220.97* 1572.25 ± 236.93* 1437.11 ± 285.83** 1478.26 ± 288.17* 1422.87 ± 198.54*
TGF-1β (pg/mg protein) 485.90 ± 91.34 1237.05 ± 125.78# 702.38 ± 98.77* 598.11 ± 212.45* 474.03 ± 102.76** 552.03 ± 203.84* 492.11 ± 88.16*
  1. The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test