Skip to main content

International Journal of Phytomedicine and Phytotherapy

Table 9 Effect of AKSS16-LIV01 on TNF α and TGF 1β levels in liver tissue in chronic ethanol-induced hepatic damage in mice

From: Antioxidant and immunomodulatory effect of AKSS16-LIV01 – a multi herbal formulation against ethanol induced liver dysfunction in mice

Parameters

Normal

Ethanol

Ethanol + AKSS16-LIV01 (75)

Ethanol+AKSS16-LIV01 (150)

Ethanol+AKSS16-LIV01 (300)

Ethanol + Silymarin (100)

AKSS16-LIV01 (300)

TNF-α (pg/mg protein)

1411.91 ± 206.53

2344.77 ± 371.98#

1636.77 ± 220.97*

1572.25 ± 236.93*

1437.11 ± 285.83**

1478.26 ± 288.17*

1422.87 ± 198.54*

TGF-1β (pg/mg protein)

485.90 ± 91.34

1237.05 ± 125.78#

702.38 ± 98.77*

598.11 ± 212.45*

474.03 ± 102.76**

552.03 ± 203.84*

492.11 ± 88.16*

  1. The values are expressed as the mean ± SEM. Significantly different from control #p < 0.001 and significantly different from ethanol*p < 0.05, **p < 0.001using analysis of variance (ANOVA) followed by Dunnettʼs Multiple Comparison Test