Plate 2

Photomicrograph Sections of the Kidneys of Streptozotocin induced Diabetic Rats fed on a High Fat Diet. A = Glibenclamide (10 mg/kg): Features reveal visible renal corpuscles (long arrow), interstitial spaces (short arrow) and tubules with diffused mononuclear infiltrates. B = Negative control (untreated): Shows visible renal corpuscles (long arrow), interstitial spaces (short arrow) and tubules showing tubular necrosis. C = S. jamaicensis extract (30 mg/kg): Reveals visible renal corpuscles (long arrow) with pyknotic nucleus and visible tubules (short arrow). D = S. jamaicensis extract (50 mg/kg): Section shows visible renal corpuscles with pyknotic nucleus (long arrow) and visible tubules (short arrow). E = S. jamaicensis extract (100 mg/kg): Shows visible renal corpuscles (long arrow) with mild inflammatory cells surrounding it (short arrow) and the tubules appeared not so distinct. [H & E staining; × 40 magnification]