Anti-diuretic and anti-glycemic properties of Jatropha gossypiifolia L. leave extract on wistar rats

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 5 Effect of Jatropha gossypiifolia L. on renal function test on day 14

Groups	Doses (mg/kg)	Creatinine mg/dl Mean ± SEM	Urea mg/dl Mean ± SEM	Bicarbonate (HCO₃) mmol/L Mean ± SEM	Sodium (Na⁺⁾ mmol/L Mean ± SEM	Potassium (K⁺⁾ mmol/L Mean ± SEM	Chloride (Cl^-) mmol/L Mean ± SEM
Control (STZ)	40	0.28 ± 0.00 ^a	37.17 ± 5.52^a	13.50 ± 0.87^a	101.1 ± 1.31^a	19.40 ± 0.65^a	78.22 ± 3.19^a
Gliberclamide	10	0.18 ± 0.02^b	27.50 ± 1.44^a	19.17 ± 0.48^b	105.1 ± 0.95^a	23.08 ± 0.35^a	65.77 ± 4.39^a
Normal control	DW	0.21 ± 0.01^b	27.59 ± 2.55^a	18.50 ± 1.44^b	109.5 ± 1.78^b	22.00 ± 1.34^a	64.00 ± 4.07^b
J. gossypiifolia	30	0.23 ± 0.01^a	24.41 ± 0.05^b	19.75 ± 0.05^b	109.3 ± 0.14^b	24.56 ± 0.32^b	64.25 ± 1.11^b
J. gossypiifolia	50	0.22 ± 0.01^b	23.79 ± 0.36^b	18.98 ± 0.01^b	109.2 ± 0.43^b	25.50 ± 0.29^b	63.18 ± 0.15 ^b
J. gossypiifolia	100	0.26 ± 0.00^a	27.88 ± 0.26^a	17.34 ± 0.01^a	108.5 ± 0.64^b	25.32 ± 0.18^b	78.92 ± 0.44^a

p-value > superscript ^a = 0.05, ^b = 0.01 showed the level of significant difference when compared with untreated control, (n = 5). DW---- distilled water