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International Journal of Phytomedicine and Phytotherapy

Table 5 Histopathological result of rat’s kidney administered aqueous and ethanolic extract of Spondias purpurea leaf

From: Toxicological studies of aqueous and ethanol leaf extract of Spondias purpurea (red plum) in rats

Histopathological changes

C

AQ extract (mg/kg)

5,001,000 1500

ET extract (mg/kg)

5,001,000 1500

Congestion

+

+

+

+

++

+

Necrosis of renal

tubular epithelium

+

+

+

+

+

+

Widened Bowman’s space

+

+

+

+

+

+

Collapsed renal tubules

+

Mononuclear

cellular infiltration

+

+

+

+

Congested with

Hemosiderosis

+

Adhesion of the parietal layer of the glomerulus to the Bowman’s space

+

+

+

+

  1. Keys: ++ = severely present, + = present, − = absent, AQ Aqueous, ET Ethanol, C Normal control