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International Journal of Phytomedicine and Phytotherapy

Table 5 Histopathological result of rat’s kidney administered aqueous and ethanolic extract of Spondias purpurea leaf

From: Toxicological studies of aqueous and ethanol leaf extract of Spondias purpurea (red plum) in rats

Histopathological changes C AQ extract (mg/kg)
5,001,000 1500
ET extract (mg/kg)
5,001,000 1500
Congestion + + + + ++ +
Necrosis of renal
tubular epithelium
+ + + + + +
Widened Bowman’s space + + + + + +
Collapsed renal tubules +
Mononuclear
cellular infiltration
+ + + +
Congested with
Hemosiderosis
+
Adhesion of the parietal layer of the glomerulus to the Bowman’s space + + + +
  1. Keys: ++ = severely present, + = present, − = absent, AQ Aqueous, ET Ethanol, C Normal control