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International Journal of Phytomedicine and Phytotherapy

Table 7 Effect of Mystomate4® on pylorus ligation- induced ulcer in Sprague Dawley rats showing the ulcer index and percentage inhibition, gastric juice pH and its acidity level

From: Acute and sub-chronic toxicity assessment and evaluation of the gastro-protective activity of polyherbal formulation “Mystomate4® against gastric ulcer in experimental laboratory animal

Treatment

Dose (mg/kg)

Ulcer index

% Inhibition

Gastric juice (ml)

Gastric pH

Gastric acidity (meq/L)

Control

3.17 ± 0.60

0.55 ± 0.18

6.28 ± 0.39

6.67 ± 0.14

Mystomate4®

1.14

2.50 ± 0.62

54.89

0.55 ± 0.08

6.32 ± 0.31

7.83 ± 0.04

Mystomate4®

2.28

1.58 ± 0.71

65.71

0.40 ± 0.06

6.30 ± 0.17

9.00 ± 0.02

Mystomate4®

3.43

0.67 ± 0.21**

81.95

0.72 ± 0.09

5.98 ± 0.11

7.00 ± 0.08

Cimetidine

40

0.67 ± 0.33**

75.94

0.17 ± 0.09

7.12 ± 0.30

3.33 ± 0.08*

  1. The results are expressed as mean ± SEM; n = 6. * P < 0.05, ** P < 0.01, compared to control group followed by Dunnett post test