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International Journal of Phytomedicine and Phytotherapy

Table 2 Effect of treatment on serum cardiac biomarkers of studied rat groups

From: Diallyl trisulfide modulated autophagy in isoproterenol induced acute myocardial infarction

Group

Normal Control

ISO

LY294002 + ISO

DATS + ISO

CAP + ISO

DATS + ISO + LY294002

CAP + ISO+ LY294002

Serum cTnI level

198.24 ± 7.1

264.09 ± 11.76 a

253.81 ± 8.97 a

208.93 ± 37.13 b, c

215.04 ± 16.38 b.c

201.95 ± 32.8 b, c

201.79 ± 26.44 b, c

Serum CK-MB

6.6 ± 1.81

25.86 ± 3.24 a

14.86 ± 1.81 a, b

7.7 ± 0.85 b, c

7.98 ± 2.43 b, c

12.66 ± 1.35 a, b, c

11.83 ± 1.93 a, b, c

  1. Data are presented as mean ± SD, significance was set at P < 0.05, n = 6. ISO: Isoproterenol induced AMI group (85 mg/kg/d), LY294002 + ISO: PI3K inhibitor group (0.3 mg/kg/d), DATS+ISO: Diallyl trisulfide pretreated group (40 mg/kg d), CAP+ISO: Captopril pretreated group (50 mg/kg/d), DATS+LY294002 + ISO: Diallyl trisulfide and PI3K inhibitor pretreated group, CAP+LY294002 + ISO: Captopril and PI3K inhibitor pretreated group. a: Significant versus normal control group. b: Significant versus ISO group. c: Significant versus LY294002 + ISO group