Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 1 Antiplasmodial activity of purified fraction of M senegalensis leaf against Plasmodium chabaudi Infected mice

	Doses (mg/kg bw)	1	2	3	4	5	6	Mean Parasitaemia	% suppression
MS	75	130.56	120.87	134.09	100.05	88.06	79.67	108.98 ± 6.83	15.24 ± 0.89^a
	150	79.05	86.55	80.05	58.03	60.43	54.08	69.53 ± 3.45	45.70 ± 3.43 ^b
	300	80.04	84.35	70.55	60.55	49.55	56.56	66.54 ± 5.98	48.50 ± 4.56 ^b
CQ	5	36.05	42.05	58.05	40.50	22.55	18.05	21.55 ± 2.35	83.50 ± 8.89 ^c
NS	2 ml/kg	136.05	140.55	150.46	122.05	102.05	118.55	128.05 ± 9.89

Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
MS: Maytenus senegalensis (Lam.) Exell
CQ: Chloroquine
NS: Normal saline.