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International Journal of Phytomedicine and Phytotherapy

Table 1 Antiplasmodial activity of purified fraction of M senegalensis leaf against Plasmodium chabaudi Infected mice

From: Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

  Doses (mg/kg bw) 1 2 3 4 5 6 Mean Parasitaemia % suppression
MS 75 130.56 120.87 134.09 100.05 88.06 79.67 108.98 ± 6.83 15.24 ± 0.89a
  150 79.05 86.55 80.05 58.03 60.43 54.08 69.53 ± 3.45 45.70 ± 3.43 b
  300 80.04 84.35 70.55 60.55 49.55 56.56 66.54 ± 5.98 48.50 ± 4.56 b
CQ 5 36.05 42.05 58.05 40.50 22.55 18.05 21.55 ± 2.35 83.50 ± 8.89 c
NS 2 ml/kg 136.05 140.55 150.46 122.05 102.05 118.55 128.05 ± 9.89  
  1. Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
  2. MS: Maytenus senegalensis (Lam.) Exell
  3. CQ: Chloroquine
  4. NS: Normal saline.