Characterization of anti-plasmodial, analgesic and anti-inflammatory fraction of Maytenus senegalensis (lam.) Exell leaf extract in mice

Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Effect of purified fraction of M. senegalensis leaf on oedema

Extract	Doses (mg/kg bw)	20	40	60	80	100	120	Mean	Inhibition (%)
MS	75	0.32 ± 0.05	0.38 ± 0.02	0.38 ± 0.03	0.36 ± 0.02	0.38 ± 0.04	0.38 ± 0.04	0.37 ± 0.04	53.16 ± 4.09 ^a
MS	150	0.30 ± 0.03	0.36 ± 0.04	0.34 ± 0.02	0.30 ± 0.06	0.28 ± 0.03	0.30 ± 0.02	0.31 ± 0.02	60.76 ± 7.54 ^b
ASA	150	0.30 ± 0.02	0.30 ± 0.02	0.26 ± 0.04	0.28 ± 0.02	0.32 ± 0.02	0.30 ± 0.03	0.29 ± 0.06	63.29 ± 5.98 ^b
NS	2 mL/kg	0.80 ± 0.04	0.80 ± 0.03	0.76 ± 0.05	0.78 ± 0.03	0.82 ± 0.05	0.80 ± 0.05	0.79 ± 0.03

Data are MEAN ± SEM of triplicate determinations. Values followed by different superscript are significantly different (p < 0.05)
MS: Maytenus senegalensis (Lam.) Exell
ASA: Acetylsalicylic acid
NS: Normal saline