Fig. 5

Hepatic mRNA expression of SREBP-1c, ACC, FAS, PPARα, and CPT1 on day 28. Con: nondiabetic control, CCAE-Con: nondiabetic control treated with CCAE, NIA/STZ: early-stage diabetic group, CCAE-NIA/STZ: the early-stage diabetic group treated with CCAE, STZ: late-stage diabetic group, CCAE-STZ: the late-stage diabetic group treated with CCAE. *p < 0.05; ** p < 0.01; *** p < 0.001. We have presented the data as the mean ± SEM. #, p < 0.05 and ##, p < 0.01 show significant differences between the diabetic group (STZ or NIA/STZ, respectively) versus Con