Fig. 6From: Differential expression of gluconeogenic enzymes in early- and late-stage diabetes: the effect of Citrullus colocynthis (L.) Schrad. Seed extract on hyperglycemia and hyperlipidemia in Wistar-Albino rats modelEffect of CCAE on hepatic protein carbonylation and triglyceride levels. We observed increased levels of PCC (LT2D and ET2D vs. Con, p = 0.73 and p = 0.19, respectively) and TG in the liver tissue of both diabetic groups compared to Con. Treatment with CCAE led to a significant reduction of both variables in all treated groups compared to their untreated controls. Con: nondiabetic control, CCAE-Con: nondiabetic control treated with CCAE, NIA/STZ: early-stage diabetic group, CCAE-NIA/STZ: the early-stage diabetic group treated with CCAE, STZ: late-stage diabetic group, CCAE-STZ: the late-stage diabetic group treated with CCAE. we have expressed the values as mean ± SEM. *, p = 0.016; **, p = 0.008, †, p = 0.029. #, p < 0.05 and ##, p < 0.01 show significant differences between the diabetic group (STZ or NIA/STZ, respectively) versus ConBack to article page