Clinical Phytoscience

International Journal of Phytomedicine and Phytotherapy

Table 3 Fasting blood chemistry on day 28

From: Differential expression of gluconeogenic enzymes in early- and late-stage diabetes: the effect of Citrullus colocynthis (L.) Schrad. Seed extract on hyperglycemia and hyperlipidemia in Wistar-Albino rats model

	Control (not diabetic)		Early Diabetes (ET2D)		Late Diabetes (LT2D)
	Con	CCAE- Con	NIA/STZ	CCAE- NIA/STZ	STZ	CCAE -STZ
Urea	56.5 ± 5.48	49.33 ± 3.75	55.13 ± 2.92^†	62.14 ± 2.66	94.50 ± 4.88^†	95.42 ± 4.83
Creatinine	0.47 ± 0.06	0.3 ± 0	0.33 ± 0.01	0.41 ± 0.03	0.39 ± 0.03	0.44 ± 0.02
Uric acid	1.67 ± 0.02	1.83 ± 0.08	1.88 ± 0.45	3.31 ± 0.86	2.25 ± 0.23	2.36 ± 0.18
TG	123.0 ± 20.01	168.0 ± 30.61	232.8 ± 29.61	*90.71 ± 6.40*	229.5 ± 24.99	*136.91 ± 29.74*
TC	74.75 ± 11.28	89.33 ± 13.32	79.5 ± 4.77	79.14 ± 4.17	86.0 ± 4.63	79.08 ± 6.58
HDL	37.5 ± 5.29	35.66 ± 2.02	37.87 ± 2.99^†	38.85 ± 2.53	47.92 ± 1.79^†	*35.08 ± 1.20*
LDL	11.75 ± 1.60	26.67 ± 6.43	11.88 ± 0.66	*19.71 ± 1.58*	16.84 ± 0.84	20.75 ± 1.14
AST	163.75 ± 5.77	143.33 ± 36.44	152.12 ± 23.42	170.28 ± 17.38	320.61 ± 60.60	171.08 ± 13.99
ALT	62.25 ± 9.98	44.67 ± 2.33	50.0 ± 5.97^†	46.14 ± 3.13	213.30 ± 34.11^†	*76.42 ± 76.23*
ALP	750.25 ± 211.6	717.33 ± 41.39	691.25 ± 80.18^†	745 ± 80.18	3825.07 ± 337.2^†	2572.58 ± 273.5

We have presented the data as mean ± SEM. Bold means statistically significant difference versus Con. Bold and italic shows statistical significance versus untreated members of the same diabetic group. Statistical value, defined as p < 0.05, was determined by non-parametric test followed by Kruskal-Wallis test in GraphPad Prism. †Shows parameters significantly different in the blood of early and late diabetes groups concerning each other; i.e., STZ vs. NIA/STZ. All the variables are given in mg/dl except for enzyme activities that are reported in units/L

Back to article page